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NGUYEN Trung Nhan, PhD

Associate Professor,
Department of Organic Chemistry
Faculty of Chemistry

University of Science, VNUHCM
Ho Chi Minh City, Vietnam
Tel: (+84) 287 3089 899
Email:ntnhan@hcmus.edu.vn

Scientific Education

2004: PhD in Pharmaceutical Sciences, Toyama University, Japan

2000: M.Sc. in Organic chemistry, University of Science, VNU-HCM 

1996: B.Sc. in Organic chemistry, University of Science, VNU-HCM

Academic & Research Experience

Natural products and medicinal chemistry

Research Skills/Interests

Structure and biological activity of natural products and drug development

Synthetic, semi-synthetic compounds with biological activity

Publication List (selected from 2013-now)

  1. Hai Xuan Nguyen, Truong Nhat Van Do, Mai Thanh Thi Nguyen, Phu Hoang Dang, Le Huu Tho, Suresh Awale, Nhan Trung Nguyen, A New Alkenylphenol from the propolis of stingless bee Trigona minor, Natural Product Communications, 13, 69-70, 2018.
  2. Mai Thanh Thi Nguyen, Phu Hoang Dang, Tu Ngoc Nguyen, Linh Thuy Thi Bui, Hai Xuan Nguyen, Tho Huu Le, Truong Nhat Van Do, Nhan Trung Nguyen, Paratrimerins G and H, two prenylated phenolic compounds from the stems of Paramignya trimera, Phytochemistry Letters, 23, 78-82, 2018.
  3. Mao Van Can, Anh Hai Tran, Dam Minh Pham, Bao Quoc Dinh, Quan Van Le, Ba Van Nguyen, Mai Thanh Thi Nguyen, Hai Xuan Nguyen, Nhan Trung Nguyen, Hisao Nishijo, Willughbeia cochinchinensis prevents scopolamine-induced deficits in memory, spatial learning, and object recognition in rodents, Journal of Ethnopharmacology, 214, 99-105, 2018.
  4. Phu Hoang Dang, Hang Kim Thi Pham, Trong Huu Nguyen Phan, Khang Duy Huu Nguyen, Mai Thanh Thi Nguyen, Nhan Trung Nguyen, A new 20-deoxypseudojujubogenin glycoside from Bacopa monniera, Chemistry of Natural Compounds, 1, 107-109, 2018.
  5. Phu Hoang Dang, Tinh Thi Nguyen, Tho Huu Le, Hai Xuan Nguyen, Mai Thanh Thi Nguyen, Nhan Trung Nguyen, A new bischromanone from the stems of Semecarpus caudata, Natural Product Reseach, 32(15), 1745-1750, 2018.
  6. Nhan Trung Nguyen, Phu Hoang Dang, Ngoc Xuan Thi Vu, Tho Huu Le, Mai Thanh Thi Nguyen, Quinoliniumolate and 2H-1,2,3-triazole derivatives from the stem of Paramignya trimera and their α-glucosidase inhibitory activities: in vitro and in silico studies, Journal of Natural Products, 80, 2151-2155, 2017.
  7. Hai Xuan Nguyen, Mai Thanh Thi Nguyen, Nhan Trung Nguyen, Suresh Awale, Chemical Constituents of propolis from Vietnamese Trigona minor and their antiausterity activity against the PANC-1 human pancreatic cancer cell line, Journal of Natural Products, 80, 2345-2352, 2017.
  8. Phu Hoang Dang, Hanh Hong Thi Nguyen, Hien Thanh Thi Truong, Truong Nhat Van Do, Hai Xuan Nguyen, Mai Thanh Thi Nguyen, Manabu Abe, Ryukichi Takagi, Nhan Trung Nguyen, Two opened-oxetane taxoids with the C-20 benzoyloxy group from the roots of Taxus wallichiana Zucc., Tetrahedron Letters, 58, 3897-3900, 2017.
  9. Mai Thanh Thi Nguyen, Tho Huu Le, Hai Xuan Nguyen, Phu Hoang Dang, Truong Nhat Van Do, Manabu Abe, Ryukichi Takagi, Nhan Trung Nguyen, Artocarmins G–M, prenylated 4-chromenones from the stems of Artocarpus rigida and their tyrosinase inhibitory activities, Journal of Natural Products, 80, 3172-3178, 2017.
  10. Sinh Truong Nguyen, Khanh Linh Huynh, Huyen Lam-Thi Nguyen, Mai Nguyen Thi Thanh, Nhan Nguyen Trung, Hai Nguyen Xuan, Kim Phan Ngoc, Kiet Truong Dinh, Phuc Van Pham, Hopea odorata extract inhibits hepatocellular carcinoma via induction of caspase-dependent apoptosis, OncoTargets and Therapy, 10, 5765-5774, 2017.
  11. Nhan Trung Nguyen, Mai Thanh Thi Nguyen, Hai Xuan Nguyen, Phu Hoang Dang, Dya Fita Dibwe, Hiroyasu Esumi, Suresh Awale, Constituents of the rhizomes of Boesenbergia pandurata and their antiausterity activities against the PANC-1 human pancreatic cancer line, Journal of Natural Products, 80, 141-148, 2017.
  12. Phu Hoang Dang, Tho Huu Le, Phuong Kim Thi Phan, Phuong Tuyet Thi Le, Mai Thanh Thi Nguyen, Nhan Trung Nguyen, Two acridones and two coumarins from the roots of Paramignya trimera, Tetrahedron Letters, 58, 1553-1557, 2017.
  13. Phu Hoang Dang, Hai Xuan Nguyen, Truc Thanh Thi Duong, Thao Kim Thi Tran, Phuc Thi Nguyen, Trang Kieu Thi Vu, Hung Chi Vuong, Trong Huu Nguyen Phan, Mai Thanh Thi Nguyen, Nhan Trung Nguyen, Suresh Awale, α‑Glucosidase inhibitory and cytotoxic taxane diterpenoids from the stem bark of Taxus wallichiana, Journal of Natural Products, 80, 1087-1095, 2017.
  14. Khang Duy Huu Nguyen, Phu Hoang Dang, Hai Xuan Nguyen, Mai Thanh Thi Nguyen, Suresh Awale, Nhan Trung Nguyen, Phytochemical and cytotoxic studies on the leaves of Calotropis gigantea, Bioorganic & Medicinal Chemistry Letters, 27, 2902–2906, 2017.
  15. Huu Tho Le, Hai Xuan Nguyen, Truong Van Nhat Do, Phu Hoang Dang, Nhan Trung Nguyen, Mai Thanh Thi Nguyen, Moracin VN, a new tyrosinase and xanthine oxidase inhibitor from the woods of Artocarpus heterophyllus, Natural Product Communications, 12(6), 925-927, 2017.
  16. Truc Thanh Thi Duong, Truong Nhat Van Do, Hai Xuan Nguyen, Tho Huu Le, Phu Hoang Dang, Nhan Trung Nguyen, Tuyen N. T. Nguyen, Thao D. Nguyen, Mai Thanh Thi Nguyen, α-Glucosidase inhibitors from the stem of Mangifera reba, Tetrahedron Letters, 58, 2280–2283, 2017.
  17. Phu Hoang Dang, Hai Xuan Nguyen, Hanh Hong Thi Nguyen, Thai Duy Vo, Tho Huu Le, Trong Huu Nguyen Phan, Mai Thanh Thi Nguyen, Nhan Trung Nguyen, Lignans from the roots of Taxus wallichiana and their α‑glucosidase inhibitory activities, Journal of Natural Products, 80, 1876-1882, 2017.
  18. Hai Xuan Nguyen, Truong Nhat Van Do, Tho Huu Le, Mai Thanh Thi Nguyen, Nhan Trung Nguyen, Hiroyasu Esumi, Suresh Awale, Chemical constituents of Mangifera indica and their antiausterity activity against the PANC-1 human pancreatic cancer cell line, Journal of Natural Products, 79, 2053-2059, 2016.
  19. Trung Huu Bui, Nhan Trung Nguyen, Phu Hoang Dang, Hai Xuan Nguyen, Mai Thanh Thi Nguyen, Design and synthesis of chalcone derivatives as potential non-purine xanthine oxidase inhibitors, SpringerPlus, 5, 2-8, 2016.
  1. Hai Xuan Nguyen, Nhan Trung Nguyen, Phu Hoang Dang, Phuoc Thi Ho, Mai Thanh Thi Nguyen, Mao Van Can, Dya Fita Dibwe, Jun-ya Ueda, Suresh Awale, Cassane diterpenes from the seed kernels of Caesalpinia sappan, Phytochemistry, 122, 286–293, 2016.
  2. Hai Xuan Nguyen, Nhan Trung Nguyen, Mai Ha Khoa Nguyen, Tho Huu Le, Truong Nhat Van Do, Tran Manh Hung, Mai Thanh Thi Nguyen, Tyrosinase inhibitory activity of flavonoids from Artocarpus heterophyllous, Chemistry Central Journal, 10, 1-6, 2016.
  1. Hai Xuan Nguyen, Nhan Trung Nguyen, Phu Hoang Dang, Phuoc Thi Ho, Mai Thanh Thi Nguyen, Mao Van Can, Dya Fita Dibwe, Jun-ya Ueda, Kinzo Matsumoto, Suresh Awale, A new cassane-type diterpene from the seed of Caesalpinia sapan, Natural Product Communication, 11(6), 723-724, 2016.
  2. Hai Xuan Nguyen, Tri Cong Le, Truong Nhat Van Do, Tho Huu Le, Nhan Trung Nguyen, Mai Thanh Thi Nguyen, α-Glucosidase inhibitors from the bark of Mangifera mekongensis, Chemistry Central Journal, 10(45), 1-6, 2016.
  3. Linh My Thi Lam, Mai Thanh Thi Nguyen, Hai Xuan Nguyen, Phu Hoang Dang, Nhan Trung Nguyen, Hung Manh Tran, Hoa Thi Nguyen, Nui Minh Nguyen, Byung Sun Min, Jeong Ah Kim, Jae Sue Choi, Mao Van Can, Anti-cholinesterases and memory improving effects of Vietnamese Xylia xylocarpa, Chemistry Central Journal, 10(48), 2-10, 2016.
  4. Phu Hoang Dang, Mai Thanh Thi Nguyen, Hai Xuan Nguyen, Dung Thuy Thi Vu, Son Van Truong, Nhan Trung Nguyen, Three new cassane-type furanoditerpenes from the seed of Vietnamese Caesalpinia bonducella, Phytochemistry Letters, 13, 99-102, 2015.
  5. Phu Hoang Dang, Nhan Trung Nguyen, Hai Xuan Nguyen, Luan Bao Nguyen, Tho Tuong Le, Truong Nhat Van Do, Mao Van Can, Mai Thanh Thi Nguyen, α-Glucosidase Inhibitors from the Leaves of Embelia ribes, Fitoterapia, 100, 201-207, 2015.
  6. Mai Thanh Thi Nguyen, Nhan Trung Nguyen, Khang Duy Huu Nguyen, Hien Thu Thi Dau, Hai Xuan Nguyen, Phu Hoang Dang, Tam Minh Le, Trong Huu Nguyen Phan, Anh Hai Tran, Bac Duy Nguyen, Jun-ya Ueda, Suresh Awale, Geranyl dihydrochalcones from Artocarpus altilis and their antiausteric activity, Planta Medica, 80(2-3), 193-200, 2014.
  7. Phu Hoang Dang, Hai Xuan Nguyen, Nhan Trung Nguyen, Hanh Ngoc Thi Le, Mai Thanh Thi Nguyen, α-Glucosidase Inhibitors from the Stems of Embelia ribes, Phytotherapy Research, 28, 1632-1636, 2014.
  8. Tran Manh Hung, Nguyen Xuan Hai, Nguyen Trung Nhan, Ton That Quang, Tran Le Quan, To Dao Cuong, Nguyen Hai Dang, Nguyen Tien Dat, Cytotoxic activity of new phenolic compounds from Vietnamese Caesalpinia sappan, Bioscience Biotechnology and Biochemistry, 77(12), 2378-2382, 2013.
  9. Nguyen Xuan Hai, Nguyen Thi Thanh Mai, Nguyen Anh Thy, Nguyen Thi Y Nhi, Phan Thi Anh Dao, Ho Thi Phuoc, Phan Nguyen Huu Trong, Dang Hoang Phu, Nguyen Trung Nhan, Jun-ya Ueda, Suresh Awale, Cleistanthane diterpenes from the seed of Caesalpinia sappan and their antiausterity activity against PANC-1 human pancreatic cancer cell line, Fitoterapia, 91, 148-153, 2013.

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